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CsoR is a novel Mycobacterium tuberculosis copper-sensing transcriptional regulator
Tong Liu, Arati Ramesh, Zhen Ma, Sarah K Ward, Limei Zhang, Graham N George, Adel M Talaat, James C Sacchettini and David P Giedroc
Copper is an essential element that becomes highly cytotoxic when concentrations exceed the capacity of cells to sequester the ion. Here, we identify a new copper-specific repressor (CsoR) of a copper-sensitive operon (cso) in Mycobacterium tuberculosis (Mtb) that is representative of a large, previously uncharacterized family of proteins (DUF156).
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